Cryospots
Evidenz-Hub

Kryotherapie Studien — die wissenschaftliche Grundlage der Kältekammer.

Über 200 peer-reviewed Cryotherapy Studies aus 50+ Jahren klinischer und sportwissenschaftlicher Forschung — kuratiert, kategorisiert und kommentiert. Vom ersten Hokkaido-Protokoll Dr. Yamaguchis (1978) bis zu Meta-Analysen aus 2025.

208+
Studien
50
Jahre Forschung
8
Themen-Cluster

Was die Evidenz zeigt

Cryotherapy ist eine der am besten dokumentierten nicht-pharmakologischen Recovery-Methoden überhaupt. Mehr als ein halbes Jahrhundert klinischer und sportwissenschaftlicher Forschung — von Dr. Toshima Yamaguchis bahnbrechender Arbeit mit Rheuma-Patienten 1978 in Japan bis zu hochrangigen Meta-Analysen 2025 — bestätigt: Wer regelmäßig in eine Kältekammer geht, profitiert messbar.

Die Bandbreite der dokumentierten Wirkungen ist beeindruckend — und über die Studien hinweg konsistent. Whole-Body Cryotherapy reduziert Muskelkater (DOMS) nach intensivem Training, beschleunigt die Erholung zwischen Trainingseinheiten und senkt entzündungsfördernde Zytokine wie IL-6 und TNF-α nachweislich. Bei chronisch-entzündlichen Erkrankungen — rheumatoide Arthritis, Fibromyalgie, ankylosierende Spondylitis — zeigen Studien substanzielle Schmerzreduktion und Verbesserung der Lebensqualität. In der mentalen Gesundheit dokumentiert die Forschung positive Effekte auf Stimmung, Schlafqualität, Stressresilienz und Symptome leichter bis moderater Depressionen.

Wir bei Cryospots haben einen Vorteil gegenüber jedem einzelnen Cryo-Anbieter: wir verkaufen die Behandlung selbst nicht. Wir sind ein neutrales Verzeichnis. Das erlaubt uns, die Studienlage so darzustellen, wie sie ist — selbstbewusst, wo die Evidenz stark ist; nüchtern, wo Marketingclaims die Forschung überholen.

Evidenz nach Anwendungsbereich

Die acht zentralen Themen-Cluster der Cryotherapy-Forschung — klick durch zur gefilterten Studienliste.

Meistzitierte Studien

Die sechs einflussreichsten Cryotherapy-Arbeiten — gewichtet nach Zitationen und Aktualität.

471 Zitationen2004

The physiologic basis and clinical applications of cryotherapy and thermotherapy for the pain practitioner.

Cryotherapy reduces tissue metabolism and inflammation, while thermotherapy increases them, both providing significant pain relief with low side-effect profiles.

S. Nadler, K. Weingand, R. Kruse
Pain physician
372 Zitationen2010

Cryoablation: mechanism of action and devices.

Cryoablation causes tissue damage and death through direct and indirect mechanisms, with factors like cooling rate, target temperature, time at target temperature, and thawing rate influencing injury.

J. Erinjeri, T. Clark
Journal of vascular and interventional radiology : JVIRDOI ↗
328 ZitationenMeta-Analyse2018

An Evidence-Based Approach for Choosing Post-exercise Recovery Techniques to Reduce Markers of Muscle Damage, Soreness, Fatigue, and Inflammation: A Systematic Review With Meta-Analysis

Massage is the most effective method for reducing delayed onset muscle soreness and perceived fatigue after physical exercise, while compression techniques can effectively manage perceived fatigue.

O. Dupuy, W. Douzi, D. Theurot et al.
Frontiers in PhysiologyDOI ↗
372 Zitationen1996

Cryotherapy in sports medicine

Cryotherapy effectively treats acute soft tissue injuries, reduces pain, and speeds up recovery in sports medicine, with few complications or side-effects.

C. Swenson, L. Swärd, J. Karlsson
Scandinavian Journal of Medicine & Science in SportsDOI ↗
263 Zitationen2009

Experimental cryosurgery investigations in vivo.

Cryosurgery, using freezing temperatures to target targeted tissues, has advanced as a widely applied therapeutic option due to its effectiveness in cellular and tissue-related events.

A. Gage, J. Baust, J. Baust
CryobiologyDOI ↗
245 ZitationenLiteratur-Review2013

Water Immersion Recovery for Athletes: Effect on Exercise Performance and Practical Recommendations

Cold water immersion for 5-15 minutes is most effective for athletes, while both cold and warm water contrast therapy show promise for recovery, but the optimal technique remains unclear.

Nathan G. Versey, S. Halson, B. Dawson
Sports MedicineDOI ↗
Bereit für deine erste Sitzung?

Finde ein verifiziertes Cryo-Studio in deiner Nähe.

Über 280 geprüfte Kältekammer-Zentren weltweit. Adresse, Methode, Preise, Bewertungen — alles auf einen Blick.

Cryo-Center finden →

Alle Studien

53 von 208 Studien · Thema: Stimmung & Mental Health

Filter zurücksetzen
1996·372 Zit.

Cryotherapy in sports medicine

Cryotherapy effectively treats acute soft tissue injuries, reduces pain, and speeds up recovery in sports medicine, with few complications or side-effects.

C. Swenson, L. Swärd et al.DOI ↗
2009·263 Zit.

Experimental cryosurgery investigations in vivo.

Cryosurgery, using freezing temperatures to target targeted tissues, has advanced as a widely applied therapeutic option due to its effectiveness in cellular and tissue-related events.

A. Gage, J. Baust et al.DOI ↗
1986·314 Zit.

The Use of Cryotherapy in Sports Injuries

Cryotherapy positively impacts pain reduction and injury recovery in athletes, with varying effects on temperature and blood flow.

R. Meeusen, P. LievensDOI ↗
2010·227 Zit.

Whole-Body Cryotherapy in Athletes

Whole-body cryotherapy (WBC) is not harmful and does not induce negative effects in athletes, with potential benefits for pain relief and muscle recovery.

G. Banfi, G. Lombardi et al.DOI ↗
2011·223 Zit.Experimentelle Studie

Effects of Whole-Body Cryotherapy vs. Far-Infrared vs. Passive Modalities on Recovery from Exercise-Induced Muscle Damage in Highly-Trained Runners

Whole-body cryotherapy accelerates recovery from exercise-induced muscle damage more effectively than far-infrared or passive recovery modalities in highly-trained runners.

C. Hausswirth, J. Louis et al.DOI ↗
2013·171 Zit.

Cold-water immersion and other forms of cryotherapy: physiological changes potentially affecting recovery from high-intensity exercise

Cryotherapy, involving cold-water immersion and other forms, may speed recovery from high-intensity exercise by reducing tissue temperature and affecting blood flow, cell swelling, metabolism, and neural conductance velocity.

Gillian E. White, Greg D. WellsDOI ↗
2017·145 Zit.Literatur-Review

Whole-Body Cryotherapy in Athletes: From Therapy to Stimulation. An Updated Review of the Literature

Whole-body cryotherapy is a widely used sports medicine treatment that improves pain, soreness, stress, and post-exercise recovery, with potential applications in metabolic diseases like obesity and type 2 diabetes.

G. Lombardi, E. Ziemann et al.DOI ↗
2013·110 Zit.Meta-Analyse

Whole-body cryotherapy (extreme cold air exposure) for preventing and treating muscle soreness after exercise in adults.

Whole-body cryotherapy has very low quality evidence to determine its effectiveness in reducing muscle soreness and improving subjective recovery after exercise in physically active young adult males.

J. Costello, P. Baker et al.DOI ↗
2017·83 Zit.Randomisierte kontrollierte Studie

Recovery following a marathon: a comparison of cold water immersion, whole body cryotherapy and a placebo control

Whole body cryotherapy negatively impacts muscle function and perceptions of soreness after a marathon, while cryotherapy is no more effective than a placebo for improving functional recovery or perceptions of training stress.

L. Wilson, E. Cockburn et al.DOI ↗
2022·57 Zit.

Cold for centuries: a brief history of cryotherapies to improve health, injury and post-exercise recovery

Cryotherapies, using ice, cold-water, and cold air, have been used for centuries to improve health, injury recovery, and post-exercise recovery, with benefits including reduced pain and improved well-being.

R. Allan, J. Malone et al.DOI ↗
2017·68 Zit.Literatur-Review

Cold-Water Immersion for Athletic Recovery: One Size Does Not Fit All.

Cold-water immersion for athletic recovery may vary in effectiveness based on individual characteristics, water-immersion protocol, and exercise type, requiring further research to optimize prescription.

Jessica M Stephens, S. Halson et al.DOI ↗
2021·52 Zit.Randomisierte kontrollierte Studie

Cryotherapy for treatment of chronic rhinitis: 3‐month outcomes of a randomized, sham‐controlled trial

Cryotherapy is superior to a sham procedure for improving chronic rhinitis symptoms and patient quality of life at the 90-day follow-up.

Anthony G. Del Signore, J. Greene et al.DOI ↗
2018·47 Zit.Randomisierte kontrollierte Studie

Whole body cryotherapy, cold water immersion, or a placebo following resistance exercise: a case of mind over matter?

Whole body cryotherapy is more effective than cold water immersion in attenuating soreness and improving peak force after resistance training, but both treatments do not accelerate recovery more effectively than a placebo.

L. Wilson, L. Dimitriou et al.DOI ↗
2023·29 Zit.Systematisches Review

Evaluating safety risks of whole-body cryotherapy/cryostimulation (WBC): a scoping review from an international consortium

Whole-body cryotherapy (WBC) has potential benefits for improving sleep quality, neuromuscular recovery, and chronic pain relief, with safety risks within acceptable limits when adhering to existing recommendations and guidelines.

Fabien D. Legrand, Benoit Dugué et al.DOI ↗
2021·29 Zit.

Post-exercise Recovery: Cooling and Heating, a Periodized Approach

Athletes need to optimize their recovery process to reduce fatigue, injury risk, and illness, while maintaining performance and minimizing financial implications.

R. ThorpeDOI ↗
2023·20 Zit.Experimentelle Studie

Whole-Body Cryostimulation in Post-COVID Rehabilitation for Patients with Obesity: A Multidisciplinary Feasibility Study

Whole-body cryostimulation is a safe and effective rehabilitation method for obese patients with post-COVID symptoms, improving physical performance, reducing pain, and enhancing psychological well-being.

J. Fontana, Angelo Alito et al.DOI ↗
2022·22 Zit.Meta-Analyse

The effect of cold water immersion on the recovery of physical performance revisited: A systematic review with meta-analysis

Cold water immersion improves short-term recovery of endurance performance and longer-term recovery of muscle strength and power, depending on the nature of the preceding exercise.

H. Choo, Marcus Lee et al.DOI ↗
2022·21 Zit.

WHOLE-BODY CRYOSTIMULATION: A REHABILITATION BOOSTER

Whole-body cryostimulation (WBC) shows potential as an adjuvant therapy for various rehabilitation conditions, promoting recovery and restoring homeostasis.

P. Capodaglio, R. Cremascoli et al.DOI ↗
2021·23 Zit.Randomisierte kontrollierte Studie

The improvement of cognitive deficits after whole-body cryotherapy – A randomised controlled trial

Whole-body cryotherapy may improve cognitive functions and mood in individuals with mild cognitive impairment, suggesting potential as an early intervention method.

Joanna Rymaszewska, K. Lion et al.DOI ↗
2023·17 Zit.

Breast Cancer Cryoablation Fundamentals Past and Present: Technique Optimization and Imaging Pearls.

Cryoablation is an effective, safe, well-tolerated, and feasible nonsurgical treatment for early-stage breast cancer with favorable ancillary features, offering a 98% clinical success rate and potential immunological therapeutic effects.

Monica L. Huang, K. Tomkovich et al.DOI ↗
2024·12 Zit.Randomisierte kontrollierte Studie

Effects of an Early Exercise Program with Cryotherapy on Range of Motion, Pain, Swelling, and Gait in Patients with Total Knee Arthroplasty: A Randomized Controlled Trial

An early exercise program with cryotherapy effectively improves range of motion, pain, swelling, and walking in patients undergoing total knee arthroplasty.

Bomi Lee, Doyoo Yoon et al.DOI ↗
2023·12 Zit.Systematisches Review

Whole-body cryotherapy as a treatment for chronic medical conditions?

Whole-body cryotherapy shows potential as an adjuvant therapy for chronic inflammation in various medical conditions, including rheumatoid arthritis, obesity, and chronic brain disorders.

Hanna Tabisz, A. Modlińska et al.DOI ↗
2024·9 Zit.Systematisches Review

Whole-Body Cryostimulation in Multiple Sclerosis: A Scoping Review

Whole-body cryostimulation may improve functional status, mood, anxiety, and fatigue in MS patients without causing adverse effects.

Angelo Alito, J. Fontana et al.DOI ↗
2024·7 Zit.Randomisierte kontrollierte Studie

The Acute Effects of Cold Water Immersion and Percussive Massage Therapy on Neuromuscular Properties and Muscle Soreness after Exercise in Young Male Soccer Players

Percussive massage therapy and cold water immersion both improve muscle strength and reduce muscle soreness after strenuous exercise in young male soccer players.

A. Buoite Stella, Angelo Michele Dragonetti et al.DOI ↗
2021·15 Zit.Meta-Analyse

A Systematic Review and Meta-analysis of the Effect of Whole Body Cryotherapy on Mental Health Problems.

Whole body cryotherapy shows preliminary evidence as an effective add-on intervention for mental health problems, particularly depressive symptoms.

Julia J. R. Doets, M. Topper et al.DOI ↗
2023·9 Zit.Randomisierte kontrollierte Studie

Cryotherapy and pain intensity during endodontic treatment of mandibular first permanent molars with symptomatic irreversible pulpitis: A randomized controlled trial

Cryotherapy significantly improves the efficacy of inferior alveolar nerve block in endodontic treatment of primary molars with irreversible pulpitis in children, reducing pain but still requiring additional anesthesia.

A. Elheeny, Dania Ibrahem Sermani et al.DOI ↗
2024·5 Zit.

Whole-body cryotherapy in orthopaedics: current concepts

Whole-body cryotherapy shows promise in improving bone health in athletes and providing relief for osteoarthritis and fibromyalgia, but more research is needed to establish standard protocols and understand long-term effects.

Madhan Jeyaraman, Filippo Migliorini et al.DOI ↗
2024·5 Zit.Randomisierte kontrollierte Studie

The effectiveness of cryostimulation exposure on sleep and recovery in male athletes: Timing considerations

Whole-body cryostimulation after intense evening training improves sleep and recovery, with the most significant benefits occurring 1 hour before bedtime.

C. Arc-Chagnaud, Benoit Dugué et al.DOI ↗
2021·13 Zit.Experimentelle Studie

Efficacy of whole-body cryotherapy in the treatment of chronic low back pain: Quasi-experimental study.

Whole-body cryotherapy effectively reduces pain and disability in chronic low back pain patients, while also decreasing pro-inflammatory markers and increasing anti-inflammatory markers.

Ó. Salas-Fraire, J. A. Rivera-Perez et al.DOI ↗
2022·10 Zit.Experimentelle Studie

The Comparative Effect of Different Timings of Whole Body Cryotherapy Treatment With Cold Water Immersion for Post-Exercise Recovery

Whole Body Cryotherapy within an hour of exercise may be preferable for muscle strength recovery, but it is no more effective than cold water immersion for post-exercise recovery.

A. Haq, W. Ribbans et al.DOI ↗
2024·4 Zit.Experimentelle Studie

Whole-Body Cryostimulation: An Effective Complementary Treatment in Fibromyalgia? A Follow Up Study

Whole-body cryostimulation (WBC) as part of a rehabilitation program can provide stronger positive effects on improving key aspects of fibromyalgia, such as general well-being, pain level, and sleep quality, lasting 3-4 months.

Federica Verme, N. Majdič et al.DOI ↗
2025·1 Zit.

Cutaneous Cryosurgery in Dermatology: Evolving Principles and Clinical Applications for Benign, Premalignant, and Malignant Lesions

Cryosurgery is a valuable treatment option for various skin diseases due to its safety, efficiency, and cost-effectiveness, offering advantages over established treatments.

R. Mokbel, Alevtina Kodresko et al.DOI ↗
2025·1 Zit.Systematisches Review

Post-Exercise Recovery Modalities in Male and Female Soccer Players of All Ages and Competitive Levels: A Systematic Review

Cold-water immersion consistently improves jump performance and well-being in soccer players, while other recovery strategies show varying levels of effectiveness and evidence.

Emaly Vatne, J. M. Oliva-Lozano et al.DOI ↗
2025·1 Zit.Literatur-Review

Isolated and Combined Effects of Cold, Heat and Hypoxia Therapies on Muscle Recovery Following Exercise-Induced Muscle Damage

Cold, heat, and hypoxia therapies can effectively aid muscle recovery from exercise-induced damage, with heat therapy being the most effective method for restoring muscle function.

Yohan Rousse, Benoît Sautillet et al.DOI ↗
2025Systematisches Review

Optimizing Chronic Pain Treatment: A Summary of Infrequently Investigated Therapeutic Interventions for Modulating Pain.

Resistance training, fasting therapy, sauna therapy, and cryotherapy show promising results for chronic pain disorders, with potential mechanisms including central processes, peripheral mechanisms, neurotransmitters, nervous system activation, and mood enhancement.

Andrew J Ordille, Michael Sabia et al.
2025Literatur-Review

The Comprehensive Evolution of Cryotherapy: A Review on Mechanisms, Applications and the Future of Cold Therapy from Sports Medicine to Metabolic Health

Cryotherapy effectively reduces pain and edema, improves recovery, and enhances mental well-being, but protocol standardization and long-term molecular and psychological effects require further research.

Cihangir AçıkDOI ↗
2025Randomisierte kontrollierte Studie

Effect of pneumatic and cold compression on muscle performance and recovery in combat sports athletes

Pneumatic and cold compression therapies accelerate recovery in combat athletes by improving blood flow and muscle elasticity, potentially improving performance and reducing injury risk.

R. Trybulski, Sebastian Klich et al.DOI ↗
2024·2 Zit.Meta-Analyse

The effectiveness of cryotherapy and cooled topical anesthesia compared with conventional topical anesthesia in alleviating intraoral injection pain: A systematic review and meta-analysis.

Cryotherapy significantly reduces intraoral injection pain compared to topical anesthesia, particularly for children and combined age groups, but is less effective in adults.

Pooya Saeedi, Alireza Sarraf Shirazi et al.DOI ↗
2024Systematisches Review

CRYOTHERAPY IN THE FIELD OF ENDODONTICS: A LITERATURE REVIEW

Cryotherapy can effectively control postoperative pain and inflammation in endodontics, reducing nerve conduction velocity and promoting local anti-inflammation.

Amena Al Bast, R. AbiadDOI ↗
2023·1 Zit.

The PRICE of Injury Treatment: Out With the Old and In With the New

The POLICE approach combines ice, compression, and elevation to effectively address pain and return patients to their pre-injury activities, while incorporating optimal loading techniques to facilitate healing.

C. BusbyDOI ↗
2019·12 Zit.Systematisches Review

Cryotherapy duration is critical in short-term recovery of athletes: a systematic review

Cryotherapy for athletes should be limited to 11-15 minutes in cold water, with cold water immersion providing greater benefits than passive recovery.

Alexander H. Jinnah, T. D. Luo et al.DOI ↗
2021·6 Zit.Systematisches Review

Cryosurgery and physical medicine n treatment of cancer

Cryosurgery combined with other physical medicine techniques can enhance the effectiveness of treating cancer patients by maximizing the potential for exposure of biological tissues to low temperatures.

M. Chyzh, I. Belochkina et al.DOI ↗
2021·5 Zit.Systematisches Review

Pre-Exercise Whole- or Partial-Body Cryotherapy Exposure to Improve Physical Performance: A Systematic Review

Pre-exercise whole- or partial-body cryotherapy exposure has unclear potential for improving physical performance, with limited good-quality research and lack of standardization of protocols.

Emily M Partridge, J. Cooke et al.DOI ↗
2022

H12: Campbell De Morgan: doctor, scientist, polymath

Cryotherapy, using low temperatures to destroy tissue, has evolved over the last 200 years, with advances in liquid nitrogen, solid carbon dioxide, and liquid oxygen, and its use expanded to treat various diseases and neoplasms.

A. Abdullah, L. O’Higgins et al.DOI ↗
2022

H11: A chilling history of cryotherapy

Cryotherapy, using low temperatures to destroy tissue, has evolved over the last 200 years, with advances in liquid nitrogen, solid carbon dioxide, and liquid oxygen, and its use expanded to treat various diseases and neoplasms.

A. Abdullah, L. O’Higgins et al.DOI ↗
2022

H13: Dermatological surgery through time: how sustainable are we now?

Cryotherapy has evolved over time to treat various skin conditions, with liquid nitrogen being the most effective and advancing technology in the 21st century.

A. Abdullah, L. O’Higgins et al.DOI ↗
2021·2 Zit.

Cryotherapy in sport: a warm reception for the translation of evidence into applied practice

Cryotherapy's role in sport injury management is unclear, and future study designs should reflect current demands and individual responses for improved evidence translation.

J. Alexander, Dr Robert Allan et al.DOI ↗
2021Randomisierte kontrollierte Studie

Cold therapy promotes self-limited recovery of delayed-onset muscle soreness

Cold therapy, such as ice massage and immersion in cold water, can promote self-limited recovery of delayed-onset muscle soreness after high-intensity eccentric exercise.

X. Jiang, Hai-Xia Zhu et al.DOI ↗
2019Randomisierte kontrollierte Studie

The impact of cryotherapy versus placebo interventions on recovery following strenuous exercise, and adaptations to resistance training

Cryotherapy is no more effective than a placebo for functional recovery or attenuating inflammation after acute endurance or resistance exercise, and repeated exposure may cause maladaptive hypertrophic responses.

L. Wilson
2018Literatur-Review

CRYOSURGERY DEVELOPING

Cryosurgery has developed since the 19th century, but its effectiveness in various medical fields is limited by a lack of understanding of tissue damage mechanisms and the need for better temperature control.

S. Artemev, Z. Radzhabova et al.DOI ↗
2018

Cryotherapy: The Dry Benefits

Cryotherapy accelerates muscle recovery and improves overall wellbeing, with the cryosauna device providing a safe, healthy, and effective treatment for various conditions.

D. Draper, Brock RobertsDOI ↗
2018

PO-228 Effects of Different Cryotherapy Models on Timing Sequence Recovery of Exercise Induced Muscle Damage in Middle and Long Distance Runners

Whole body cryotherapy (cryostimulation) has the best recovery effects for exercise-induced muscle damage in middle and long distance runners compared to cold water immersion and contrast water therapy.

Chaoyi Qu, Minxiao Xu et al.DOI ↗
2015

An evaluation of the benefits of whole body cryotherapy treatment for sports recovery and injury repair

Whole Body Cryotherapy may promote recovery from strenuous exercise and enhance sports performance, but more research is needed to determine its timing, effectiveness, and potential negative effects on chronic adaptations to training.

A. Haq, W. Ribbans et al.

Die Wissenschaft ist eindeutig. Probier es selbst aus.

Cryospots listet hunderte verifizierte Kältekammer-Zentren in Deutschland, Österreich, der Schweiz, den USA und 30+ weiteren Ländern.